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Association of Factors With Elevated Amyloid Burden in Clinically Normal Older Individuals

June 1, 2020

Authors: Reisa A Sperling, Michael C Donohue, Rema Raman, Chung-Kai Sun, Roy Yaari, Karen Holdridge, Eric Siemers, Keith A Johnson, Paul S Aisen, A4 Study Team

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Trial of Solanezumab in Preclinical Alzheimer’s Disease

July 17, 2023

Authors: Reisa A. Sperling, M.D., Michael C. Donohue, Ph.D., Rema Raman, Ph.D., Michael S. Rafii, M.D., Ph.D., Keith Johnson, M.D., Colin L. Masters, M.D., Christopher H. van Dyck, M.D., Takeshi Iwatsubo, M.D., Gad A. Marshall, M.D., Roy Yaari, M.D., Michele Mancini, M.D., Karen C. Holdridge, M.P.H., Michael Case, M.S., John R. Sims, M.D., and Paul S. Aisen, M.D., for the A4 Study Team

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July 24, 2024

Amyloid and Tau Prediction of Cognitive and Functional Decline in Unimpaired Older Individuals: Longitudinal Data from the A4 and LEARN Studies

Sperling RA, Donohue MC, Rissman RA, Johnson KA, Rentz DM, Grill JD, Heidebrink JL, Jenkins C, Jimenez-Maggiora G, Langford O, Liu A, Raman R, Yaari R, Holdridge KC, Sims JR, Aisen PS

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July 24, 2024

Characterizing Clinical Progression in Cognitively Unimpaired Older Individuals with Brain Amyloid: Results from the A4 Study

Rentz DM, Rosenberg PB, Sperling RA, Donohue MC, Raman R, Liu A, Aisen PS

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July 24, 2024

Longitudinal Phospho-tau217 Predicts Amyloid Positron Emission Tomography in Asymptomatic Alzheimer's Disease

Rissman RA, Donohue MC, Langford O, Raman R, Abdel-Latif S, Yaari R, Holdridge KC, Sims JR, Molina-Henry D, Jimenez-Maggiora G, Johnson KA, Aisen PS, Sperling RA

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July 24, 2024

Relationship between Plasma P-Tau217 and Amyloid PET in Racial and Ethnic Underrepresented Groups (RE-URG) Compared with Non RE-URG in LEARN and A4

Molina-Henry D, Langford O, Donohue MC, Raman R, Aisen P, Johnson KA, Rissman RA, Sperling R

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July 24, 2024

Longitudinal Trajectories of the Cognitive Function Index in the A4 Study

Amariglio RE, Grill JD, Rentz DM, Marshall GA, Donohue MC, Liu A, Aisen PS, Sperling RA

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July 24, 2024

Change in Digital Cognitive Test Performance between Solanezumab and Placebo Groups in Preclinical Alzheimer's Disease: Secondary Analyses from the A4 Study

Papp KV, Maruff P, Rentz DM, Donohue MC, Liu A, Aisen PS, Sperling RA

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